Spiral galaxies in Leo
Messier 65 is on the right. Along with a third spiral galaxy, NGC 3628 (to their north and outside the frame of this image), they form the well-known Leo Trio. They can be easily seen in the same telescopic field of view with a low-power eyepiece.
Image details: Exposure times of 81 minutes luminance, and 30 minutes each of red, green, and blue, taken with an SBIG ST-8300M imager and a 14" Meade LX850 telescope at f/4.8.